Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| H | 0004252 | molecular_function | serine-type endopeptidase activity |
| H | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue NH4 A 301 |
| Chain | Residue |
| A | ARG24 |
| A | LYS175 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue NH4 A 302 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue NH4 B 101 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide CSA B 1 and VAL B 2 |
| Chain | Residue |
| A | GLN118 |
| B | ASN3 |
| B | CYS7 |
| B | NH4101 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide CSA B 1 and CYS B 7 |
| Chain | Residue |
| A | LYS192 |
| A | GLY218 |
| B | VAL2 |
| B | ASN3 |
| B | ILE4 |
| B | MET5 |
| B | CSA6 |
| B | ARG8 |
| B | CYS9 |
| B | NH4101 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide MET B 5 and CSA B 6 |
| Chain | Residue |
| A | HIS57 |
| A | ALA97 |
| A | GLU98 |
| A | TYR171 |
| A | HIS174 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | GLU217 |
| B | ASN3 |
| B | ILE4 |
| B | CYS7 |
| B | ARG8 |
| B | CYS9 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide CSA B 6 and CYS B 9 |
| Chain | Residue |
| A | HIS57 |
| A | ALA97 |
| A | LYS192 |
| A | SER195 |
| A | SER214 |
| B | ASN3 |
| B | ILE4 |
| B | MET5 |
| B | CYS7 |
| B | ARG8 |
| B | PRO10 |
| B | NH211 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for Di-peptide CSA B 6 and CYS B 7 |
| Chain | Residue |
| A | HIS57 |
| A | ALA97 |
| A | LYS192 |
| A | SER214 |
| A | GLY218 |
| B | CSA1 |
| B | ASN3 |
| B | ILE4 |
| B | MET5 |
| B | ARG8 |
| B | CYS9 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for Di-peptide PRO B 10 and NH2 B 11 |
| Chain | Residue |
| A | ARG39 |
| A | LEU41 |
| A | LYS192 |
| A | SER195 |
| A | HOH401 |
| B | CYS9 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLS |
| Chain | Residue | Details |
| A | ASP189-SER200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | LYS107 | |
| A | LYS157 | |
| H | LYS467 | |
| H | LYS516 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLN221 | |
| H | GLN583 | |
| Chain | Residue | Details |
| A | LYS126 | |
| H | LYS486 | |
| Chain | Residue | Details |
| A | CYS168 | |
| H | CYS527 | |
