6TKA
Crystal structure of human O-GlcNAc transferase bound to substrate 7 and a peptide from HCF-1 pro-repeat 2 (11-26)
This is a non-PDB format compatible entry.
Summary for 6TKA
Entry DOI | 10.2210/pdb6tka/pdb |
Descriptor | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, HCF-1 pro-repeat 2 (11-26), [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{S},6~{R})-3-[6-(butanoylamino)hexanoylamino]-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] hydrogen phosphate, ... (5 entities in total) |
Functional Keywords | transferase complex o-glcnac ogt, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 84066.30 |
Authors | Meek, R.W.,Davies, G.J. (deposition date: 2019-11-28, release date: 2020-03-04, Last modification date: 2024-01-24) |
Primary citation | Alteen, M.G.,Gros, C.,Meek, R.W.,Cardoso, D.A.,Busmann, J.A.,Sangouard, G.,Deen, M.C.,Tan, H.Y.,Shen, D.L.,Russell, C.C.,Davies, G.J.,Robinson, P.J.,McCluskey, A.,Vocadlo, D.J. A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High-Throughput Screening: Application to O-GlcNAc Transferase. Angew.Chem.Int.Ed.Engl., 59:9601-9609, 2020 Cited by PubMed: 32092778DOI: 10.1002/anie.202000621 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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