6TKA
Crystal structure of human O-GlcNAc transferase bound to substrate 7 and a peptide from HCF-1 pro-repeat 2 (11-26)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 727 | 81389.0 | 1 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | Homo sapiens (Human) | O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,OGT |
| 2 | B (BBB) | HCF-1 pro-repeat 2 (11-26) | polymer | 16 | 1608.6 | 1 | Homo sapiens | ||
| 3 | C (AAA) | [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{S},6~{R})-3-[6-(butanoylamino)hexanoylamino]-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] hydrogen phosphate | non-polymer | 748.6 | 1 | Chemie (NJ5) | |||
| 4 | D (AAA) | 3-[2,2-bis(fluoranyl)-10,12-dimethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-4-yl]-~{N}-ethyl-propanamide | non-polymer | 320.2 | 1 | Chemie (NG8) | |||
| 5 | E, F (AAA, BBB) | water | water | 18.0 | 208 | Chemie (HOH) |
Sequence modifications
AAA: 313 - 1036 (UniProt: O15294)
| PDB | External Database | Details |
|---|---|---|
| Gly 310 | - | expression tag |
| Pro 311 | - | expression tag |
| Ala 312 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82997.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1068.7 | |
| All* | Total formula weight | 84066.3 |
