6TFB
Carbamazepine binds Frizzled8
Summary for 6TFB
Entry DOI | 10.2210/pdb6tfb/pdb |
Descriptor | Frizzled-8, GLYCEROL, benzo[b][1]benzazepine-11-carboxamide, ... (4 entities in total) |
Functional Keywords | wnt receptor frizzled8 carbamazepine, oncoprotein |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 32378.98 |
Authors | Zhao, Y.,Jones, E.Y. (deposition date: 2019-11-13, release date: 2020-02-26, Last modification date: 2024-01-24) |
Primary citation | Zhao, Y.,Ren, J.,Hillier, J.,Lu, W.,Jones, E.Y. Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8. J.Med.Chem., 63:3252-3260, 2020 Cited by PubMed: 32049522DOI: 10.1021/acs.jmedchem.9b02020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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