6TFB
Carbamazepine binds Frizzled8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Frizzled-8 | polymer | 138 | 15815.1 | 2 | UniProt (Q61091) Pfam (PF01392) In PDB | Mus musculus (Mouse) | mFz8 |
| 2 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | A, B | benzo[b][1]benzazepine-11-carboxamide | non-polymer | 236.3 | 2 | Chemie (N6W) | |||
| 4 | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 151 (UniProt: Q61091)
| PDB | External Database | Details |
|---|---|---|
| Glu 25 | - | expression tag |
| Thr 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Glu 49 | Asn 49 | conflict |
| Glu 152 | - | expression tag |
| Arg 153 | - | expression tag |
| Gly 154 | - | expression tag |
| Thr 155 | - | expression tag |
| Leu 156 | - | expression tag |
| Glu 157 | - | expression tag |
| Val 158 | - | expression tag |
| Leu 159 | - | expression tag |
| Phe 160 | - | expression tag |
| Gln 161 | - | expression tag |
| Gly 162 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31630.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 748.8 | |
| All* | Total formula weight | 32379.0 |
