6T92

NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex of N120C mutant protein with the reduced form of the cofactor NADH and the substrate formate at a secondary site.

This is a non-PDB format compatible entry.

Summary for 6T92

• Entry DOI: 10.2210/pdb6t92/pdb
• Descriptor: Formate dehydrogenase, DI(HYDROXYETHYL)ETHER, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (6 entities in total)
• Functional Keywords: nad+, cytosolic protein
• Biological source: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
• Total number of polymer chains: 4
• Total formula weight: 186408.71

Authors

Isupov, M.N.,Yelmazer, B.,De Rose, S.A.,Littlechild, J.A. (deposition date: 2019-10-25, release date: 2020-11-18, Last modification date: 2024-01-24)

• Primary citation: Yilmazer, B.,Isupov, M.N.,De Rose, S.A.,Bulut, H.,Benninghoff, J.C.,Binay, B.,Littlechild, J.A.; Structural insights into the NAD + -dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD + ternary complex of the Chaetomium thermophilum enzyme.; J.Struct.Biol., 212:107657-107657, 2020; PubMed: 33148525; DOI: 10.1016/j.jsb.2020.107657

Experimental method

X-RAY DIFFRACTION (1.12 Å)