6T92

NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex of N120C mutant protein with the reduced form of the cofactor NADH and the substrate formate at a secondary site.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0005737	cellular_component	cytoplasm
AAA	0005829	cellular_component	cytosol
AAA	0008863	molecular_function	formate dehydrogenase (NAD+) activity
AAA	0016491	molecular_function	oxidoreductase activity
AAA	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
AAA	0032787	biological_process	monocarboxylic acid metabolic process
AAA	0042183	biological_process	formate catabolic process
AAA	0051287	molecular_function	NAD binding
BBB	0005737	cellular_component	cytoplasm
BBB	0005829	cellular_component	cytosol
BBB	0008863	molecular_function	formate dehydrogenase (NAD+) activity
BBB	0016491	molecular_function	oxidoreductase activity
BBB	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
BBB	0032787	biological_process	monocarboxylic acid metabolic process
BBB	0042183	biological_process	formate catabolic process
BBB	0051287	molecular_function	NAD binding
CCC	0005737	cellular_component	cytoplasm
CCC	0005829	cellular_component	cytosol
CCC	0008863	molecular_function	formate dehydrogenase (NAD+) activity
CCC	0016491	molecular_function	oxidoreductase activity
CCC	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
CCC	0032787	biological_process	monocarboxylic acid metabolic process
CCC	0042183	biological_process	formate catabolic process
CCC	0051287	molecular_function	NAD binding
DDD	0005737	cellular_component	cytoplasm
DDD	0005829	cellular_component	cytosol
DDD	0008863	molecular_function	formate dehydrogenase (NAD+) activity
DDD	0016491	molecular_function	oxidoreductase activity
DDD	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
DDD	0032787	biological_process	monocarboxylic acid metabolic process
DDD	0042183	biological_process	formate catabolic process
DDD	0051287	molecular_function	NAD binding

Functional Information from PROSITE/UniProt

site_id	PS00065
Number of Residues	29
Details	D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. VGTVGvGRIGervlrrlkgfdckeLLyYD

Chain	Residue	Details
AAA	VAL168-ASP196

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site_id	PS00670
Number of Residues	23
Details	D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. MLaqCDVVtINcPlhesTrgLfN

Chain	Residue	Details
AAA	MET219-ASN241

---

site_id	PS00671
Number of Residues	17
Details	D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKrGsWLVNtARGaIVV

Chain	Residue	Details
AAA	MET248-VAL264

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	52
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03210","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Site: {"description":"Important for catalytic activity","evidences":[{"source":"HAMAP-Rule","id":"MF_03210","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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