6T92
NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex of N120C mutant protein with the reduced form of the cofactor NADH and the substrate formate at a secondary site.
This is a non-PDB format compatible entry.
Functional Information from GO Data
Chain | GOid | namespace | contents |
AAA | 0005737 | cellular_component | cytoplasm |
AAA | 0005829 | cellular_component | cytosol |
AAA | 0008863 | molecular_function | formate dehydrogenase (NAD+) activity |
AAA | 0016491 | molecular_function | oxidoreductase activity |
AAA | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
AAA | 0042183 | biological_process | formate catabolic process |
AAA | 0051287 | molecular_function | NAD binding |
BBB | 0005737 | cellular_component | cytoplasm |
BBB | 0005829 | cellular_component | cytosol |
BBB | 0008863 | molecular_function | formate dehydrogenase (NAD+) activity |
BBB | 0016491 | molecular_function | oxidoreductase activity |
BBB | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
BBB | 0042183 | biological_process | formate catabolic process |
BBB | 0051287 | molecular_function | NAD binding |
CCC | 0005737 | cellular_component | cytoplasm |
CCC | 0005829 | cellular_component | cytosol |
CCC | 0008863 | molecular_function | formate dehydrogenase (NAD+) activity |
CCC | 0016491 | molecular_function | oxidoreductase activity |
CCC | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
CCC | 0042183 | biological_process | formate catabolic process |
CCC | 0051287 | molecular_function | NAD binding |
DDD | 0005737 | cellular_component | cytoplasm |
DDD | 0005829 | cellular_component | cytosol |
DDD | 0008863 | molecular_function | formate dehydrogenase (NAD+) activity |
DDD | 0016491 | molecular_function | oxidoreductase activity |
DDD | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
DDD | 0042183 | biological_process | formate catabolic process |
DDD | 0051287 | molecular_function | NAD binding |
Functional Information from PROSITE/UniProt
site_id | PS00065 |
Number of Residues | 29 |
Details | D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. VGTVGvGRIGervlrrlkgfdckeLLyYD |
Chain | Residue | Details |
AAA | VAL168-ASP196 |
site_id | PS00670 |
Number of Residues | 23 |
Details | D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. MLaqCDVVtINcPlhesTrgLfN |
Chain | Residue | Details |
AAA | MET219-ASN241 |
site_id | PS00671 |
Number of Residues | 17 |
Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKrGsWLVNtARGaIVV |
Chain | Residue | Details |
AAA | MET248-VAL264 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 32 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03210 |
Chain | Residue | Details |
AAA | ILE94 | |
BBB | CYS120 | |
BBB | ARG175 | |
BBB | ASP196 | |
BBB | PRO231 | |
BBB | THR257 | |
BBB | ASP283 | |
BBB | HIS312 | |
CCC | ILE94 | |
CCC | CYS120 | |
CCC | ARG175 | |
AAA | CYS120 | |
CCC | ASP196 | |
CCC | PRO231 | |
CCC | THR257 | |
CCC | ASP283 | |
CCC | HIS312 | |
DDD | ILE94 | |
DDD | CYS120 | |
DDD | ARG175 | |
DDD | ASP196 | |
DDD | PRO231 | |
AAA | ARG175 | |
DDD | THR257 | |
DDD | ASP283 | |
DDD | HIS312 | |
AAA | ASP196 | |
AAA | PRO231 | |
AAA | THR257 | |
AAA | ASP283 | |
AAA | HIS312 | |
BBB | ILE94 |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | SITE: Important for catalytic activity => ECO:0000255|HAMAP-Rule:MF_03210 |
Chain | Residue | Details |
AAA | ARG259 | |
AAA | HIS312 | |
BBB | ARG259 | |
BBB | HIS312 | |
CCC | ARG259 | |
CCC | HIS312 | |
DDD | ARG259 | |
DDD | HIS312 |