6T92
NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex of N120C mutant protein with the reduced form of the cofactor NADH and the substrate formate at a secondary site.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (AAA, BBB, CCC, DDD) | Formate dehydrogenase | polymer | 410 | 45630.4 | 4 | UniProt (G0SGU4) Pfam (PF00389) Pfam (PF02826) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | FDH,NAD-dependent formate dehydrogenase |
| 2 | E, F, P, T, U (AAA, CCC, DDD) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) PubChem (8117) | |||
| 3 | G, L, Q, V (AAA, BBB, CCC, DDD) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 4 | Chemie (NAI) PubChem (928) PubChem (11250888) PubChem (12309341) PubChem (16219774) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (94865921) PubChem (94865923) PubChem (124432988) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875) | |||
| 4 | H, M, N, R, S... (AAA, BBB, CCC, DDD) | FORMIC ACID | non-polymer | 46.0 | 7 | Chemie (FMT) PubChem (284) | |||
| 5 | I, J, K, O, Y... (AAA, BBB, DDD) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | AA, BA, CA, DA (AAA, BBB, CCC, DDD) | water | water | 18.0 | 1759 | Chemie (HOH) |
Sequence modifications
AAA, BBB, CCC, DDD: 1 - 370 (UniProt: G0SGU4)
| PDB | External Database | Details |
|---|---|---|
| Met -33 | - | initiating methionine |
| Ala -32 | - | expression tag |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| Val -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Thr -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Ser -21 | - | expression tag |
| Asn -20 | - | expression tag |
| Asp -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Lys -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Pro -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Pro -11 | - | expression tag |
| Asn -10 | - | expression tag |
| Trp -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Thr -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Gln 0 | - | expression tag |
| Cys 120 | Asn 120 | engineered mutation |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 182521.8 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 3886.9 | |
| All* | Total formula weight | 186408.7 |
