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6SYP

Human DHODH bound to inhibitor IPP/CNRS-A017

This is a non-PDB format compatible entry.
Summary for 6SYP
Entry DOI10.2210/pdb6syp/pdb
DescriptorDihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ... (6 entities in total)
Functional Keywordsdihydroorotate dehydrogenase inhibitor complex, structural genomics, structural genomics consortium, sgc, oxidoreductase
Biological sourceHomo sapiens
Total number of polymer chains1
Total formula weight44041.10
Authors
Kraemer, A.,Janin, Y.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-09-30, release date: 2019-10-09, Last modification date: 2024-01-24)
Primary citationKramer, A.,Kurz, C.G.,Berger, B.T.,Celik, I.E.,Tjaden, A.,Greco, F.A.,Knapp, S.,Hanke, T.
Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor
Eur.J.Med.Chem., 208:112770-, 2020
Cited by
DOI: 10.1016/j.ejmech.2020.112770
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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