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6ST2

Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs

Summary for 6ST2
Entry DOI10.2210/pdb6st2/pdb
DescriptorBcl-2-like protein 1, Affimer AF6, SULFATE ION, ... (4 entities in total)
Functional Keywordsaffimer, protein binding
Biological sourceHomo sapiens (Human)
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Total number of polymer chains4
Total formula weight56629.52
Authors
Hobor, F.,Miles, J.A.,Trinh, C.H.,Taylor, J.,Tiede, C.,Rowell, P.R.,Jackson, B.,Nadat, F.,Kyle, H.F.,Wicky, B.I.M.,Clarke, J.,Tomlinson, D.C.,Wilson, A.J.,Edwards, T.A. (deposition date: 2019-09-09, release date: 2020-09-30, Last modification date: 2024-01-24)
Primary citationMiles, J.A.,Hobor, F.,Trinh, C.H.,Taylor, J.,Tiede, C.,Rowell, P.R.,Jackson, B.R.,Nadat, F.A.,Ramsahye, P.,Kyle, H.F.,Wicky, B.I.M.,Clarke, J.,Tomlinson, D.C.,Wilson, A.J.,Edwards, T.A.
Selective Affimers Recognise the BCL-2 Family Proteins BCL-x L and MCL-1 through Noncanonical Structural Motifs*.
Chembiochem, 22:232-240, 2021
Cited by
PubMed: 32961017
DOI: 10.1002/cbic.202000585
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.79 Å)
Structure validation

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