6ST2
Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bcl-2-like protein 1 | polymer | 153 | 17506.5 | 2 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) | Homo sapiens (Human) | Bcl2-L-1,Apoptosis regulator Bcl-X |
| 2 | C, D (C, D) | Affimer AF6 | polymer | 91 | 10760.2 | 2 | synthetic construct | ||
| 3 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 153 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| - | Phe 27 | deletion |
| - | Ser 28 | deletion |
| - | Asp 29 | deletion |
| - | Val 30 | deletion |
| - | Glu 31 | deletion |
| - | Glu 32 | deletion |
| - | Asn 33 | deletion |
| - | Arg 34 | deletion |
| - | Thr 35 | deletion |
| - | Glu 36 | deletion |
| - | Ala 37 | deletion |
| - | Pro 38 | deletion |
| - | Glu 39 | deletion |
| - | Gly 40 | deletion |
| - | Thr 41 | deletion |
| - | Glu 42 | deletion |
| - | Ser 43 | deletion |
| - | Glu 44 | deletion |
| - | Met 45 | deletion |
| - | Glu 46 | deletion |
| - | Thr 47 | deletion |
| - | Pro 48 | deletion |
| - | Ser 49 | deletion |
| - | Ala 50 | deletion |
| - | Ile 51 | deletion |
| - | Asn 52 | deletion |
| - | Gly 53 | deletion |
| - | Asn 54 | deletion |
| - | Pro 55 | deletion |
| - | Ser 56 | deletion |
| - | Trp 57 | deletion |
| - | His 58 | deletion |
| - | Leu 59 | deletion |
| - | Ala 60 | deletion |
| - | Asp 61 | deletion |
| - | Ser 62 | deletion |
| - | Pro 63 | deletion |
| - | Ala 64 | deletion |
| - | Val 65 | deletion |
| - | Asn 66 | deletion |
| - | Gly 67 | deletion |
| - | Ala 68 | deletion |
| - | Thr 69 | deletion |
| - | Gly 70 | deletion |
| - | His 71 | deletion |
| - | Ser 72 | deletion |
| - | Ser 73 | deletion |
| - | Ser 74 | deletion |
| - | Leu 75 | deletion |
| - | Asp 76 | deletion |
| - | Ala 77 | deletion |
| - | Arg 78 | deletion |
| - | Glu 79 | deletion |
| - | Val 80 | deletion |
| - | Ile 81 | deletion |
| - | Pro 82 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56533.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 56629.5 |
