6SSH
Structure of the TSC2 GAP domain
Summary for 6SSH
| Entry DOI | 10.2210/pdb6ssh/pdb |
| Descriptor | GTPase activator-like protein, 1,2-ETHANEDIOL (3 entities in total) |
| Functional Keywords | gtpase activating protein, signaling protein |
| Biological source | Chaetomium thermophilum |
| Total number of polymer chains | 1 |
| Total formula weight | 23679.03 |
| Authors | Hansmann, P.,Kiontke, S.,Kummel, D. (deposition date: 2019-09-06, release date: 2020-05-27, Last modification date: 2024-01-24) |
| Primary citation | Hansmann, P.,Bruckner, A.,Kiontke, S.,Berkenfeld, B.,Seebohm, G.,Brouillard, P.,Vikkula, M.,Jansen, F.E.,Nellist, M.,Oeckinghaus, A.,Kummel, D. Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations. Structure, 28:933-942.e4, 2020 Cited by PubMed: 32502382DOI: 10.1016/j.str.2020.05.008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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