6SHC
Crystal structure of human IRE1 luminal domain Q105C
Summary for 6SHC
Entry DOI | 10.2210/pdb6shc/pdb |
Descriptor | Serine/threonine-protein kinase/endoribonuclease IRE1 (1 entity in total) |
Functional Keywords | ire1, unfolded protein response, er stress, protein quality control, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 41006.37 |
Authors | |
Primary citation | Amin-Wetzel, N.,Neidhardt, L.,Yan, Y.,Mayer, M.P.,Ron, D. Unstructured regions in IRE1 alpha specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR. Elife, 8:-, 2019 Cited by PubMed: 31873072DOI: 10.7554/eLife.50793 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.55 Å) |
Structure validation
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