6SHC
Crystal structure of human IRE1 luminal domain Q105C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase/endoribonuclease IRE1 | polymer | 367 | 41006.4 | 1 | UniProt (O75460) | Homo sapiens (Human) | Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a |
Sequence modifications
A: 24 - 390 (UniProt: O75460)
| PDB | External Database | Details |
|---|---|---|
| Cys 105 | Gln 105 | engineered mutation |
| Ser 109 | Cys 109 | engineered mutation |
| Ser 148 | Cys 148 | engineered mutation |
| Ser 332 | Cys 332 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41006.4 | |
| All* | Total formula weight | 41006.4 |
