6S9J

Crystal structure of TfR1 mimicry in complex with GP1 from MACV

Summary for 6S9J

• Entry DOI: 10.2210/pdb6s9j/pdb
• Descriptor: Pre-glycoprotein polyprotein GP complex, Transferrin receptor 1,Transferrin receptor 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: immunotherapy, glycoprotein, viral, viral protein
• Biological source: Machupo virus (MACV); More
• Total number of polymer chains: 8
• Total formula weight: 157978.86

Authors

Diskin, R.,Cohen-Dvashi, H. (deposition date: 2019-07-15, release date: 2020-01-15, Last modification date: 2024-01-24)

• Primary citation: Cohen-Dvashi, H.,Amon, R.,Agans, K.N.,Cross, R.W.,Borenstein-Katz, A.,Mateo, M.,Baize, S.,Padler-Karavani, V.,Geisbert, T.W.,Diskin, R.; Rational design of universal immunotherapy for TfR1-tropic arenaviruses.; Nat Commun, 11:67-67, 2020; PubMed: 31900422; DOI: 10.1038/s41467-019-13924-6

Experimental method

X-RAY DIFFRACTION (2.698 Å)