6S0S
The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel, ribostamycin B and 2-oxoglutarate
Summary for 6S0S
Entry DOI | 10.2210/pdb6s0s/pdb |
Descriptor | Kanamycin B dioxygenase, NICKEL (II) ION, 2-OXOGLUTARIC ACID, ... (6 entities in total) |
Functional Keywords | non-heme iron dioxygenase, alpha-ketoglutarate dioxygenase, kanamycin biosynthesis, kanj, oxidoreductase, 2-oxoglutarate, ribostamycin b, metal binding protein |
Biological source | Streptomyces kanamyceticus |
Total number of polymer chains | 6 |
Total formula weight | 195108.54 |
Authors | Mrugala, B.,Porebski, P.J.,Niedzialkowska, E.,Minor, W.,Borowski, T. (deposition date: 2019-06-18, release date: 2020-07-08, Last modification date: 2024-01-24) |
Primary citation | Mrugala, B.,Milaczewska, A.,Porebski, P.J.,Niedzialkowska, E.,Guzik, M.,Minor, W.,Borowski, T. A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J., 288:1366-1386, 2021 Cited by PubMed: 32592631DOI: 10.1111/febs.15462 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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