6RYF
High-resolution crystal structure of ERAP1 in complex with 15mer phosphinic peptide
Summary for 6RYF
Entry DOI | 10.2210/pdb6ryf/pdb |
Related | 6RQX |
Descriptor | Endoplasmic reticulum aminopeptidase 1, PSE-ARG-ILE-GLN-ARG-ALA-PHE-VAL-THR-ILE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | endoplasmic reticulum aminopeptidase 1, erap1, antigen presentation, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 107084.04 |
Authors | Giastas, P.,Stratikos, E. (deposition date: 2019-06-10, release date: 2019-12-18, Last modification date: 2024-01-24) |
Primary citation | Giastas, P.,Mpakali, A.,Papakyriakou, A.,Lelis, A.,Kokkala, P.,Neu, M.,Rowland, P.,Liddle, J.,Georgiadis, D.,Stratikos, E. Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1. Proc.Natl.Acad.Sci.USA, 2019 Cited by PubMed: 31843903DOI: 10.1073/pnas.1912070116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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