6RYF
High-resolution crystal structure of ERAP1 in complex with 15mer phosphinic peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Endoplasmic reticulum aminopeptidase 1 | polymer | 894 | 102208.5 | 1 | UniProt (Q9NZ08) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) In PDB | Homo sapiens (Human) | ARTS-1,Adipocyte-derived leucine aminopeptidase,A-LAP,Aminopeptidase PILS,Puromycin-insensitive leucyl-specific aminopeptidase,PILS-AP,Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator |
| 2 | G | PSE-ARG-ILE-GLN-ARG-ALA-PHE-VAL-THR-ILE | polymer | 14 | 1767.1 | 1 | UniProt (by SIFTS) (P04578) In PDB | Human immunodeficiency virus 1 | |
| 3 | B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | A | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 21 | Chemie (EDO) | |||
| 7 | A | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 8 | A | PROPANOIC ACID | non-polymer | 74.1 | 1 | Chemie (PPI) | |||
| 9 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 10 | water | water | 18.0 | 589 | Chemie (HOH) |
Sequence modifications
A: 46 - 938 (UniProt: Q9NZ08)
| PDB | External Database | Details |
|---|---|---|
| Arg 939 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 103975.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 2259.6 | |
| All* | Total formula weight | 107084.0 |
