6RIR

Crystal structure of phosphorylated Rab8a in complex with the Rab-binding domain of RILPL2

Summary for 6RIR

Entry DOI	10.2210/pdb6rir/pdb
Descriptor	Ras-related protein Rab-8A, RILP-like protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	membrane trafficking, rab gtpase, effector, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	54037.42
Authors	Waschbusch, D.,Purlyte, E.,Alessi, D.R.,Khan, A.R. (deposition date: 2019-04-25, release date: 2020-01-29, Last modification date: 2024-01-24)
Primary citation	Waschbusch, D.,Purlyte, E.,Pal, P.,McGrath, E.,Alessi, D.R.,Khan, A.R. Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2. Structure, 28:406-417.e6, 2020 Cited by PubMed: 32017888 DOI: 10.1016/j.str.2020.01.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.767 Å)

Structure validation