6RIJ

CDK2/cyclin A2 in complex with open-ring 5-nitrosopyrimidine inhibitor LC436

Summary for 6RIJ

• Entry DOI: 10.2210/pdb6rij/pdb
• Descriptor: Cyclin-dependent kinase 2, Cyclin-A2, 4-[[[5-nitroso-2-[[(2~{R})-1-oxidanylbutan-2-yl]amino]-6-(propan-2-ylamino)pyrimidin-4-yl]amino]methyl]phenol, ... (6 entities in total)
• Functional Keywords: cyclin-dependent kinase, purine inhibitor mimics, 5-nitrosopyrimidines, cell cycle
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 128744.90

Authors

Skerlova, J.,Rezacova, P.,Brynda, J. (deposition date: 2019-04-24, release date: 2020-07-22, Last modification date: 2024-11-20)

• Primary citation: Skerlova, J.,Rezacova, P.,Brynda, J.; CDK2/cyclin A2 in complex with open-ring 5-nitrosopyrimidine inhibitor LC436; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)