6RD1

Ruminococcus gnavus sialic acid aldolase catalytic lysine mutant in complex with sialic acid

Summary for 6RD1

• Entry DOI: 10.2210/pdb6rd1/pdb
• Related: 6RAB 6RB7
• Descriptor: Putative N-acetylneuraminate lyase, 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid (3 entities in total)
• Functional Keywords: neu5ac, sialic acid, aldolase, lyase, ruminococcus gnavus
• Biological source: [Ruminococcus] gnavus ATCC 29149
• Total number of polymer chains: 2
• Total formula weight: 74825.65

Authors

Owen, C.D.,Bell, A.,Juge, N.,Walsh, M.A. (deposition date: 2019-04-12, release date: 2019-09-25, Last modification date: 2024-01-24)

• Primary citation: Bell, A.,Brunt, J.,Crost, E.,Vaux, L.,Nepravishta, R.,Owen, C.D.,Latousakis, D.,Xiao, A.,Li, W.,Chen, X.,Walsh, M.A.,Claesen, J.,Angulo, J.,Thomas, G.H.,Juge, N.; Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.; Nat Microbiol, 4:2393-2404, 2019; PubMed: 31636419; DOI: 10.1038/s41564-019-0590-7

Experimental method

X-RAY DIFFRACTION (1.892 Å)