6RD1

Ruminococcus gnavus sialic acid aldolase catalytic lysine mutant in complex with sialic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Putative N-acetylneuraminate lyase	polymer	336	37103.6	2	UniProt (A7B555) Pfam (PF00701)	[Ruminococcus] gnavus ATCC 29149
2	C, D (A, B)	5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid	non-polymer		309.3	2	Chemie (SI3)
3	E, F (A, B)	water	water		18.0	280	Chemie (HOH)

Sequence modifications

A, B: 1 - 305 (UniProt: A7B555)

PDB	External Database	Details
Met -30	-	initiating methionine
Ser -29	-	expression tag
Tyr -28	-	expression tag
Tyr -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
Asp -20	-	expression tag
Tyr -19	-	expression tag
Asp -18	-	expression tag
Ile -17	-	expression tag
Pro -16	-	expression tag
Thr -15	-	expression tag
Thr -14	-	expression tag
Glu -13	-	expression tag
Asn -12	-	expression tag
Leu -11	-	expression tag
Tyr -10	-	expression tag
Phe -9	-	expression tag
Gln -8	-	expression tag
Gly -7	-	expression tag
Ala -6	-	expression tag
Met -5	-	expression tag
Ala -4	-	expression tag
Asp -3	-	expression tag
Ile -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 167	Lys 177	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74207.1
Non-Polymers*	Number of molecules	2
	Total formula weight	618.5
All*	Total formula weight	74825.6

*Water molecules are not included.