Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008747 | molecular_function | N-acetylneuraminate lyase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008747 | molecular_function | N-acetylneuraminate lyase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019262 | biological_process | N-acetylneuraminate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue SI3 A 401 |
| Chain | Residue |
| A | ALA13 |
| A | GLU195 |
| A | GLY210 |
| A | GLY211 |
| A | TYR257 |
| A | HOH502 |
| A | HOH524 |
| A | TYR45 |
| A | GLY48 |
| A | SER49 |
| A | SER50 |
| A | TYR139 |
| A | SER169 |
| A | GLY192 |
| A | ASP194 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue SI3 B 401 |
| Chain | Residue |
| B | ALA13 |
| B | TYR45 |
| B | GLY48 |
| B | SER49 |
| B | SER50 |
| B | TYR139 |
| B | SER169 |
| B | GLY192 |
| B | ASP194 |
| B | GLU195 |
| B | GLY210 |
| B | GLY211 |
| B | THR212 |
| B | TYR257 |
| B | HOH503 |
| B | HOH524 |
| B | HOH563 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01237","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate","evidences":[{"source":"HAMAP-Rule","id":"MF_01237","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31636419","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RD1","evidenceCode":"ECO:0007744"}]} |
