6RCT

Crystal structure of CLK3 in complex with T3-CLK

Summary for 6RCT

• Entry DOI: 10.2210/pdb6rct/pdb
• Descriptor: Dual specificity protein kinase CLK3, 4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{N}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: clk3, splicing kinase, probe, kinase inhibitor, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 86222.66

Authors

Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-04-11, release date: 2019-05-01, Last modification date: 2024-01-24)

• Primary citation: Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of CLK3 in complex with TP003; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.32 Å)