6RCT
Crystal structure of CLK3 in complex with T3-CLK
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dual specificity protein kinase CLK3 | polymer | 360 | 42318.4 | 2 | UniProt (P49761) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 3 |
| 2 | C, J (A, B) | 4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{N}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide | non-polymer | 482.6 | 2 | Chemie (JWN) | |||
| 3 | D, E, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 4 | O, P (A, B) | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A, B: 127 - 484 (UniProt: P49761)
| PDB | External Database | Details |
|---|---|---|
| Ser 125 | - | expression tag |
| Met 126 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84636.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1585.8 | |
| All* | Total formula weight | 86222.7 |
