6Q20
Crystal structure of human 1E01 Fab in complex with influenza virus neuraminidase from A/Japan/305/1957 (H2N2)
Summary for 6Q20
Entry DOI | 10.2210/pdb6q20/pdb |
Descriptor | Neuraminidase, 1E01 Fab kappa light chain, 1E01 Fab IgG1 heavy chain, ... (8 entities in total) |
Functional Keywords | broadly protective human antibody, neuraminidase, inhibition, active site, antibody-neuraminidase complex, viral protein, hydrolase-immune system complex, hydrolase/immune system |
Biological source | Influenza A virus (strain A/Japan/305/1957 H2N2) More |
Total number of polymer chains | 3 |
Total formula weight | 95205.56 |
Authors | Zhu, X.,Wilson, I.A. (deposition date: 2019-08-06, release date: 2019-10-23, Last modification date: 2023-10-11) |
Primary citation | Stadlbauer, D.,Zhu, X.,McMahon, M.,Turner, J.S.,Wohlbold, T.J.,Schmitz, A.J.,Strohmeier, S.,Yu, W.,Nachbagauer, R.,Mudd, P.A.,Wilson, I.A.,Ellebedy, A.H.,Krammer, F. Broadly protective human antibodies that target the active site of influenza virus neuraminidase. Science, 366:499-504, 2019 Cited by PubMed: 31649200DOI: 10.1126/science.aay0678 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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