6Q20
Crystal structure of human 1E01 Fab in complex with influenza virus neuraminidase from A/Japan/305/1957 (H2N2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Neuraminidase | polymer | 393 | 43496.3 | 1 | UniProt (C7RWN0) Pfam (PF00064) UniProt (by SIFTS) (Q1K9Q1) In PDB | Influenza A virus (strain A/Japan/305/1957 H2N2) | |
| 2 | L | 1E01 Fab kappa light chain | polymer | 216 | 23707.4 | 1 | Homo sapiens (Human) | ||
| 3 | H | 1E01 Fab IgG1 heavy chain | polymer | 240 | 26041.0 | 1 | Homo sapiens (Human) | ||
| 4 | B | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G46836GH) | |||
| 5 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 82 - 469 (UniProt: C7RWN0)
| PDB | External Database | Details |
|---|---|---|
| Gly 77 | - | expression tag |
| Ser 78 | - | expression tag |
| Pro 79 | - | expression tag |
| Ser 80 | - | expression tag |
| Arg 81 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 93244.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1659.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 301.4 | |
| All* | Total formula weight | 95205.6 |
