6PZV
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
Summary for 6PZV
Entry DOI | 10.2210/pdb6pzv/pdb |
Descriptor | Ubiquitin, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ... (6 entities in total) |
Functional Keywords | dna methylation, dna methyltransferase 1, histone modification, ubiquitylation, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 96785.46 |
Authors | |
Primary citation | Ren, W.,Fan, H.,Grimm, S.A.,Guo, Y.,Kim, J.J.,Yin, J.,Li, L.,Petell, C.J.,Tan, X.F.,Zhang, Z.M.,Coan, J.P.,Gao, L.,Cai, L.,Detrick, B.,Cetin, B.,Cui, Q.,Strahl, B.D.,Gozani, O.,Wang, Y.,Miller, K.M.,O'Leary, S.E.,Wade, P.A.,Patel, D.J.,Wang, G.G.,Song, J. Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation. Proc.Natl.Acad.Sci.USA, 117:18439-18447, 2020 Cited by PubMed: 32675241DOI: 10.1073/pnas.2009316117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.01 Å) |
Structure validation
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