6PW3
LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG)
Summary for 6PW3
Entry DOI | 10.2210/pdb6pw3/pdb |
Descriptor | La-related protein 1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | heat-like, cap-binding, top mrna, translation regulation, rna binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 80047.99 |
Authors | Lahr, R.M.,Berman, A.J. (deposition date: 2019-07-22, release date: 2019-11-06, Last modification date: 2023-10-11) |
Primary citation | Cassidy, K.C.,Lahr, R.M.,Kaminsky, J.C.,Mack, S.,Fonseca, B.D.,Das, S.R.,Berman, A.J.,Durrant, J.D. Capturing the Mechanism Underlying TOP mRNA Binding to LARP1. Structure, 27:1771-, 2019 Cited by PubMed: 31676287DOI: 10.1016/j.str.2019.10.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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