6PKG

Zebrafish N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) catalytic domain auto-inhibited by pro-peptide

Summary for 6PKG

Entry DOI	10.2210/pdb6pkg/pdb
Descriptor	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	uncovering enzyme, mannose 6-phosphate, glycosidase, pro-peptide, hydrolase
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	2
Total formula weight	83168.94
Authors	Gorelik, A.,Illes, K.,Nagar, B. (deposition date: 2019-06-29, release date: 2020-02-19, Last modification date: 2020-07-29)
Primary citation	Gorelik, A.,Illes, K.,Nagar, B. Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme. Structure, 28:426-436.e3, 2020 Cited by PubMed: 32109365 DOI: 10.1016/j.str.2020.02.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation