6PKG

Zebrafish N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) catalytic domain auto-inhibited by pro-peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	polymer	321	35633.7	2	UniProt (F1QSF9) Pfam (PF09992) In PDB	Danio rerio (Zebrafish)
2	C	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	1	In PDB GlyTouCan (G82348BZ)
3	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
4	B, A	IODIDE ION	non-polymer		126.9	48	Chemie (IOD)
5	A, B	molecular iodine	non-polymer		253.8	15	Chemie (I2I)
6	A	HEXAETHYLENE GLYCOL	non-polymer		282.3	1	Chemie (P6G)
7		water	water		18.0	257	Chemie (HOH)

Sequence modifications

A, B: 26 - 336 (UniProt: F1QSF9)

PDB	External Database	Details
Asp 16	-	expression tag
Arg 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
Lys 24	-	expression tag
Leu 25	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71267.5
Branched	Number of molecules	1
	Total formula weight	1057.0
Non-Polymers*	Number of molecules	67
	Total formula weight	10844.5
All*	Total formula weight	83168.9

*Water molecules are not included.