6PIT
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with SRC2 Stapled Peptide 41A and Estradiol
Summary for 6PIT
| Entry DOI | 10.2210/pdb6pit/pdb |
| Descriptor | Estrogen receptor, Stapled Peptide 41A, ESTRADIOL, ... (5 entities in total) |
| Functional Keywords | hormone, nuclear receptor, estrogen, stapled peptide, transcription |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 63616.96 |
| Authors | Fanning, S.W.,Montgomery, J.E.,Greene, G.L.,Moellering, R.E. (deposition date: 2019-06-27, release date: 2019-10-16, Last modification date: 2023-11-15) |
| Primary citation | Montgomery, J.E.,Donnelly, J.A.,Fanning, S.W.,Speltz, T.E.,Shangguan, X.,Coukos, J.S.,Greene, G.L.,Moellering, R.E. Versatile Peptide Macrocyclization with Diels-Alder Cycloadditions. J.Am.Chem.Soc., 141:16374-16381, 2019 Cited by PubMed: 31523967DOI: 10.1021/jacs.9b07578 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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