6P68

Crystal structure of FGFR1-Y563C (FGFR4 surrogate) covalently bound to compound 22.

Summary for 6P68

• Entry DOI: 10.2210/pdb6p68/pdb
• Descriptor: Fibroblast growth factor receptor 1, N-{3-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-1-(2-hydroxyethyl)-1H-pyrazol-4-yl}prop-2-enamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: transferase-transfer complex, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 107072.20

Authors

Larsen, N.A. (deposition date: 2019-06-03, release date: 2019-06-19, Last modification date: 2024-11-06)

• Primary citation: Larsen, N.A.; To be published; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)