6OZG

Crystal structure of Thermotoga maritima (Tm) Endonuclease V (E89Q) in complex with a 12mer DNA containing an inosine followed by a ribo-adenosine

Summary for 6OZG

• Entry DOI: 10.2210/pdb6ozg/pdb
• Descriptor: Endonuclease V, DNA/RNA (5'-D(*AP*AP*TP*GP*A)-R(P*A)-D(P*GP*AP*T)-R(P*NP*N)-D(P*T)-3'), MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: nucleic acid hydrolysis, rna recognition, metal ion dependent catalysis, dna damage, adenosine deamination, hydrolase
• Biological source: Thermotoga maritima; More
• Total number of polymer chains: 4
• Total formula weight: 58419.38

Authors

Samara, N.L.,Yang, W. (deposition date: 2019-05-15, release date: 2019-09-04, Last modification date: 2023-10-11)

• Primary citation: Wu, J.,Samara, N.L.,Kuraoka, I.,Yang, W.; Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.; Mol.Cell, 76:44-, 2019; PubMed: 31444105; DOI: 10.1016/j.molcel.2019.06.046

Experimental method

X-RAY DIFFRACTION (1.93 Å)