6OZG
Crystal structure of Thermotoga maritima (Tm) Endonuclease V (E89Q) in complex with a 12mer DNA containing an inosine followed by a ribo-adenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Endonuclease V | polymer | 224 | 25487.8 | 2 | UniProt (Q9X2H9) Pfam (PF04493) | Thermotoga maritima | Deoxyinosine 3'endonuclease,Deoxyribonuclease V,DNase V |
| 2 | C, D (C, D) | DNA/RNA (5'-D(*AP*AP*TP*GP*A)-R(P*A)-D(P*GP*AP*T)-R(P*NP*N)-D(P*T)-3') | polymer | 12 | 3500.3 | 2 | synthetic construct | ||
| 3 | E, F, I (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | G, L (B, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | H, J, K (B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 224 (UniProt: Q9X2H9)
| PDB | External Database | Details |
|---|---|---|
| Gln 89 | Glu 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57976.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 443.3 | |
| All* | Total formula weight | 58419.4 |
