6OAZ

Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells

Summary for 6OAZ

• Entry DOI: 10.2210/pdb6oaz/pdb
• Descriptor: Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: lipase, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 263358.39

Authors

Arora, R.,Horton, P.A.,Benson, T.E.,Romanowski, M.J. (deposition date: 2019-03-19, release date: 2019-05-08, Last modification date: 2023-10-11)

• Primary citation: Arora, R.,Nimonkar, A.V.,Baird, D.,Wang, C.,Chiu, C.H.,Horton, P.A.,Hanrahan, S.,Cubbon, R.,Weldon, S.,Tschantz, W.R.,Mueller, S.,Brunner, R.,Lehr, P.,Meier, P.,Ottl, J.,Voznesensky, A.,Pandey, P.,Smith, T.M.,Stojanovic, A.,Flyer, A.,Benson, T.E.,Romanowski, M.J.,Trauger, J.W.; Structure of lipoprotein lipase in complex with GPIHBP1.; Proc.Natl.Acad.Sci.USA, 116:10360-10365, 2019; PubMed: 31072929; DOI: 10.1073/pnas.1820171116

Experimental method

X-RAY DIFFRACTION (3.04 Å)