6OAZ
Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Lipoprotein lipase | polymer | 448 | 50465.1 | 4 | UniProt (P06858) Pfam (PF00151) Pfam (PF01477) In PDB | Homo sapiens (Human) | LPL |
2 | E, F, G, H | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 | polymer | 131 | 14727.8 | 4 | UniProt (Q8IV16) Pfam (PF00021) In PDB | Homo sapiens (Human) | GPI-anchored HDL-binding protein 1,High density lipoprotein-binding protein 1 |
3 | D, A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
4 | D, A, B, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
5 | D, A, B, C | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
6 | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
E, F, G, H: 21 - 151 (UniProt: Q8IV16)
PDB | External Database | Details |
---|---|---|
Asp 78 | Asn 78 | engineered mutation |
Asp 82 | Asn 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 260771.6 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 2586.8 | |
All* | Total formula weight | 263358.4 |