6OAZ
Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Lipoprotein lipase | polymer | 448 | 50465.1 | 4 | UniProt (P06858) Pfam (PF00151) Pfam (PF01477) | Homo sapiens (Human) | LPL |
| 2 | E, F, G, H (E, F, G, H) | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 | polymer | 131 | 14727.8 | 4 | UniProt (Q8IV16) Pfam (PF00087) | Homo sapiens (Human) | GPI-anchored HDL-binding protein 1,High density lipoprotein-binding protein 1 |
| 3 | AA, BA, I, J, O... (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 4 | CA, DA, K, L, Q... (D, A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | EA, FA, M, N, S... (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 6 | GA, HA, IA, JA (A, B, C, D) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
E, F, G, H: 21 - 151 (UniProt: Q8IV16)
| PDB | External Database | Details |
|---|---|---|
| Asp 78 | Asn 78 | engineered mutation |
| Asp 82 | Asn 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 260771.6 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2586.8 | |
| All* | Total formula weight | 263358.4 |
