6O54
Crystal Structure of multi-drug resistant HIV-1 protease PR-S17 (D25N)
Summary for 6O54
Entry DOI | 10.2210/pdb6o54/pdb |
Related | 5T2E |
Descriptor | HIV-1 protease, CHLORIDE ION (3 entities in total) |
Functional Keywords | hiv protease, hydrolase, viral protein |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 1 |
Total formula weight | 10932.42 |
Authors | Wang, Y.-F.,Brothers, R.,Agniswamy, J.,Weber, I.T. (deposition date: 2019-03-01, release date: 2019-06-19, Last modification date: 2023-10-11) |
Primary citation | Agniswamy, J.,Kneller, D.W.,Brothers, R.,Wang, Y.F.,Harrison, R.W.,Weber, I.T. Highly Drug-Resistant HIV-1 Protease Mutant PRS17 Shows Enhanced Binding to Substrate Analogues. Acs Omega, 4:8707-8719, 2019 Cited by PubMed: 31172041DOI: 10.1021/acsomega.9b00683 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.21 Å) |
Structure validation
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