6O54
Crystal Structure of multi-drug resistant HIV-1 protease PR-S17 (D25N)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | HIV-1 protease | polymer | 99 | 10790.6 | 1 | UniProt (I7BFC3) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | B, C, D, E (X) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 3 | F (X) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
X: 1 - 99 (UniProt: I7BFC3)
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Asp 25 | engineered mutation |
| Leu 46 | Met 46 | engineered mutation |
| Val 48 | Gly 48 | engineered mutation |
| Ala 67 | Cys 67 | engineered mutation |
| Ile 77 | Val 77 | engineered mutation |
| Ser 82 | Ala 82 | engineered mutation |
| Leu 93 | Ile 93 | engineered mutation |
| Ala 95 | Cys 95 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10790.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 141.8 | |
| All* | Total formula weight | 10932.4 |
