Summary for 6O1G
| Entry DOI | 10.2210/pdb6o1g/pdb |
| Related | 5TZ9 6BFP |
| Descriptor | Plasma kallikrein, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(6-amino-2,4-dimethylpyridin-3-yl)methyl]-1-({4-[(1H-pyrazol-1-yl)methyl]phenyl}methyl)-1H-pyrazole-4-carboxamide, ... (4 entities in total) |
| Functional Keywords | protease, blood clotting |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 72310.52 |
| Authors | Partridge, J.R.,Choy, R.M. (deposition date: 2019-02-19, release date: 2019-03-06, Last modification date: 2020-07-29) |
| Primary citation | Partridge, J.R.,Choy, R.M.,Silva-Garcia, A.,Yu, C.,Li, Z.,Sham, H.,Metcalf, B. Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition. J.Struct.Biol., 206:170-182, 2019 Cited by PubMed: 30876891DOI: 10.1016/j.jsb.2019.03.001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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