6BFP
Bovine trypsin bound to potent inhibitor
Summary for 6BFP
| Entry DOI | 10.2210/pdb6bfp/pdb |
| Related | 5TZ9 6ESO |
| Descriptor | Cationic trypsin, CALCIUM ION, 3-{2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl}-6-[(cyclopropylmethyl)carbamoyl]pyridine-2-carboxylic acid, ... (4 entities in total) |
| Functional Keywords | trypsin protease, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Bos taurus (Bovine) |
| Total number of polymer chains | 1 |
| Total formula weight | 23877.91 |
| Authors | Partridge, J.R.,Choy, R.M. (deposition date: 2017-10-26, release date: 2018-10-31, Last modification date: 2023-10-04) |
| Primary citation | Partridge, J.R.,Choy, R.M.,Silva-Garcia, A.,Yu, C.,Li, Z.,Sham, H.,Metcalf, B. Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition. J.Struct.Biol., 206:170-182, 2019 Cited by PubMed: 30876891DOI: 10.1016/j.jsb.2019.03.001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.292 Å) |
Structure validation
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