6O03
Monobody (MC17) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL
Summary for 6O03
Entry DOI | 10.2210/pdb6o03/pdb |
Descriptor | E3 ubiquitin-protein ligase CBL, Monobody (MC17) (2 entities in total) |
Functional Keywords | monobody, sh2 domain, e3 ligase, inhibitor, synthetic binder, protein binding, transferase-protein binding, inhibitor complex, transferase/protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 91455.06 |
Authors | Kukenshoner, T.,Pojer, F.,Hantschel, O. (deposition date: 2019-02-15, release date: 2020-08-19, Last modification date: 2024-03-13) |
Primary citation | Kukenshoner, T.,Pojer, F.,Hantschel, O. Monobody (MC17) bound to tyrosine kinase binding domain of E3 ligase CBL To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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