6NQA
Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 1-to-1 complex
Summary for 6NQA
Entry DOI | 10.2210/pdb6nqa/pdb |
EMDB information | 0468 0480 9384 |
Descriptor | 601 DNA Strand 1, 601 DNA Strand 2, Histone H4, ... (9 entities in total) |
Functional Keywords | ubiquitin, nucleosome, methyltransferase, structural protein-transferase-dna complex, structural protein/transferase/dna |
Biological source | synthetic construct More |
Total number of polymer chains | 12 |
Total formula weight | 254982.29 |
Authors | Worden, E.J.,Hoffmann, N.A.,Wolberger, C. (deposition date: 2019-01-19, release date: 2019-02-20, Last modification date: 2020-01-08) |
Primary citation | Worden, E.J.,Hoffmann, N.A.,Hicks, C.W.,Wolberger, C. Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L. Cell, 176:1490-1501.e12, 2019 Cited by PubMed: 30765112DOI: 10.1016/j.cell.2019.02.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.54 Å) |
Structure validation
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