6N3P

Crosslinked AcpP=FabZ complex from E. coli Type II FAS

Summary for 6N3P

Descriptor3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, Acyl carrier protein, N~3~-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-(3-{[(1Z)-pent-1-en-1-yl]sulfonyl}propyl)-beta-alaninamide, ... (4 entities in total)
Functional Keywordsfatty acid biosynthsis, fas, dehydratase, crosslinking, acyl carrier protein, acp, fabz, acpp, e. coli, biosynthetic protein
Biological sourceEscherichia coli
Total number of polymer chains12
Total molecular weight159421.26
Authors
Smith, J.L.,Dodge, G.J. (deposition date: 2018-11-15, release date: 2019-03-13, Last modification date: 2019-04-10)
Primary citation
Dodge, G.J.,Patel, A.,Jaremko, K.L.,McCammon, J.A.,Smith, J.L.,Burkart, M.D.
Structural and dynamical rationale for fatty acid unsaturation inEscherichia coli.
Proc. Natl. Acad. Sci. U.S.A., 116:6775-6783, 2019
PubMed: 30872475 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1818686116
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2549 0.2% 2.2% 7.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution