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6MWJ

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in complex with ligand HGN-0863

Summary for 6MWJ
Entry DOI10.2210/pdb6mwj/pdb
Descriptor2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ... (5 entities in total)
Functional Keywordsssgcid, structural genomics, seattle structural genomics center for infectious disease, lyase
Biological sourceBurkholderia pseudomallei (strain 1710b)
Total number of polymer chains3
Total formula weight53140.51
Authors
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-10-29, release date: 2019-11-06, Last modification date: 2023-10-11)
Primary citationAbendroth, J.,Dranow, D.M.,Pierce, P.G.,Horn, J.R.,Hagen, T.J.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.
Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in complex with ligand HGN-0456.
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

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