6MWJ
Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in complex with ligand HGN-0863
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | polymer | 166 | 17495.9 | 3 | UniProt (Q3JRA0) Pfam (PF02542) | Burkholderia pseudomallei (strain 1710b) | MECPS |
| 2 | D, G, I (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E (A) | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | non-polymer | 222.2 | 1 | Chemie (AZM) | |||
| 4 | F, H, J (A, B, C) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 5 | K, L, M (A, B, C) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 162 (UniProt: Q3JRA0)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 52487.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 652.9 | |
| All* | Total formula weight | 53140.5 |
