6MPX

Twelve chloride ions induce formation and stabilize the NC1 hexamer of collagen IV assembled from transition state trimers

Summary for 6MPX

Descriptorfusion protein of non-collagenous domains of collagen type IV, CHLORIDE ION, SULFATE ION, ... (8 entities in total)
Functional Keywordsstructural protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight78197.83
Authors
Bauer, R.,Boudko, S.P.,Hudson, B.G. (deposition date: 2018-10-09, release date: 2019-04-03, Last modification date: 2019-12-25)
Primary citation
Pedchenko, V.,Bauer, R.,Pokidysheva, E.N.,Al-Shaer, A.,Forde, N.R.,Fidler, A.L.,Hudson, B.G.,Boudko, S.P.
A chloride ring is an ancient evolutionary innovation mediating the assembly of the collagen IV scaffold of basement membranes.
J.Biol.Chem., 294:7968-7981, 2019
PubMed: 30923125 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA119.007426
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.17520 0.4% 3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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