6MPX

Twelve chloride ions induce formation and stabilize the NC1 hexamer of collagen IV assembled from transition state trimers

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005201	molecular_function	extracellular matrix structural constituent
A	0005581	cellular_component	collagen trimer

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CL A 701

Chain	Residue
A	ASN66
A	ALA186
A	TYR636

---

site_id	AC2
Number of Residues	4
Details	binding site for residue CL A 702

Chain	Residue
A	ARG402
A	ARG523
A	ASP525
A	GLY625

---

site_id	AC3
Number of Residues	4
Details	binding site for residue CL A 703

Chain	Residue
A	TYR412
A	ASN513
A	TYR408
A	ALA409

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CL A 704

Chain	Residue
A	TYR189
A	TYR288
A	ASN290
A	ALA633

---

site_id	AC5
Number of Residues	5
Details	binding site for residue CL A 705

Chain	Residue
A	ALA74
A	ARG76
A	ASN77
A	ASP78
A	HOH935

---

site_id	AC6
Number of Residues	7
Details	binding site for residue CL A 706

Chain	Residue
A	ALA298
A	SER299
A	ARG300
A	ASN301
A	ASP302
A	HOH873
A	HOH1001

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 A 707

Chain	Residue
A	GLN422
A	SER423
A	PHE424
A	ARG549
A	HOH847

---

site_id	AC8
Number of Residues	9
Details	binding site for residue SO4 A 708

Chain	Residue
A	ALA212
A	GLY213
A	GLU214
A	LEU215
A	ARG216
A	HOH826
A	HOH874
A	HOH958
A	HOH1094

---

site_id	AC9
Number of Residues	8
Details	binding site for residue SO4 A 709

Chain	Residue
A	ALA659
A	GLY660
A	GLU661
A	LEU662
A	ARG663
A	HOH814
A	HOH869
A	HOH995

---

site_id	AD1
Number of Residues	4
Details	binding site for residue SO4 A 710

Chain	Residue
A	ARG179
A	LYS651
A	LYS651
A	HOH867

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 A 711

Chain	Residue
A	SER579
A	GLY580
A	ARG675

---

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 A 712

Chain	Residue
A	TYR28
A	HIS29
A	HOH892

---

site_id	AD4
Number of Residues	2
Details	binding site for residue SO4 A 713

Chain	Residue
A	ARG10
A	HOH815

---

site_id	AD5
Number of Residues	5
Details	binding site for residue SO4 A 714

Chain	Residue
A	GLU197
A	ARG198
A	ARG280
A	HOH810
A	HOH822

---

site_id	AD6
Number of Residues	2
Details	binding site for residue PEG A 715

Chain	Residue
A	ILE67
A	HOH1142

---

site_id	AD7
Number of Residues	7
Details	binding site for residue PGE A 716

Chain	Residue
A	PRO86
A	GLU87
A	TYR184
A	PRO291
A	HOH1004
A	HOH1090
A	HOH1120

---

site_id	AD8
Number of Residues	6
Details	binding site for residue P6G A 717

Chain	Residue
A	ASN66
A	ASN68
A	ALA186
A	ASN290
A	GLY292
A	HOH845

---

site_id	AD9
Number of Residues	8
Details	binding site for residue GOL A 718

Chain	Residue
A	GLY213
A	THR418
A	ILE419
A	PRO420
A	GLN425
A	HIS441
A	PHE520
A	HOH836

---

site_id	AE1
Number of Residues	5
Details	binding site for residue GOL A 719

Chain	Residue
A	GLU421
A	GLY426
A	SER427
A	HOH838
A	HOH863

---

site_id	AE2
Number of Residues	2
Details	binding site for residue GOL A 720

Chain	Residue
A	TYR475
A	HIS476

---

site_id	AE3
Number of Residues	6
Details	binding site for residue GOL A 721

Chain	Residue
A	HOH802
A	HOH886
A	HOH1014
A	VAL120
A	HIS121
A	TRP252

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Cross-link: {"description":"S-Lysyl-methionine sulfilimine (Met-Lys) (interchain with K-1651)","evidences":[{"source":"PubMed","id":"12011424","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"S-Lysyl-methionine sulfilimine (Lys-Met) (interchain with M-1533)","evidences":[{"source":"PubMed","id":"12011424","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"3'-bromotyrosine","evidences":[{"source":"PubMed","id":"32571911","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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