6MPX
Twelve chloride ions induce formation and stabilize the NC1 hexamer of collagen IV assembled from transition state trimers
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | fusion protein of non-collagenous domains of collagen type IV | polymer | 693 | 76309.6 | 1 | UniProt (P02462) UniProt (P08572) Pfam (PF01413) In PDB | Homo sapiens (Human) | Collagen alpha-2(IV) chain,Collagen alpha-1(IV) chain |
2 | A | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
5 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
6 | A | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
7 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
8 | water | water | 18.0 | 440 | Chemie (HOH) |
Sequence modifications
A: -2 - 226 (UniProt: P02462)
A: 229 - 449 (UniProt: P08572)
A: 452 - 676 (UniProt: P02462)
PDB | External Database | Details |
---|---|---|
Ala -16 | - | expression tag |
Pro -15 | - | expression tag |
Leu -14 | - | expression tag |
Ala -13 | - | expression tag |
Asp -12 | - | expression tag |
Tyr -11 | - | expression tag |
Lys -10 | - | expression tag |
Asp -9 | - | expression tag |
Asp -8 | - | expression tag |
Asp -7 | - | expression tag |
Asp -6 | - | expression tag |
Lys -5 | - | expression tag |
Leu -4 | - | expression tag |
Ala -3 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 450 | - | linker |
Pro 451 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 227 | - | linker |
Thr 228 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 76309.6 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 1888.2 | |
All* | Total formula weight | 78197.8 |