6MN8

Crystal Structure of Prolyl-tRNA Synthetase from Onchocerca volvulus with bound Halofuginone and nucleotide

Summary for 6MN8

• Entry DOI: 10.2210/pdb6mn8/pdb
• Descriptor: Uncharacterized protein, MAGNESIUM ION, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ... (9 entities in total)
• Functional Keywords: ssgcid, prors, atp-binding, aminoacylation, halofuginone, structural genomics, seattle structural genomics center for infectious disease, ligase
• Biological source: Onchocerca volvulus
• Total number of polymer chains: 1
• Total formula weight: 60148.37

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-10-01, release date: 2018-10-17, Last modification date: 2023-10-11)

• Primary citation: Dranow, D.M.,Conrady, D.G.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal Structure of Prolyl-tRNA Synthetase from Onchocerca volvulus with bound Halofuginone and nucleotide; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.35 Å)